If you know what non-alcoholic fatty liver disease is, it might be because you’re one of the 25% of people worldwide who have it, according to the Cleveland Clinic. It is also something that people of all ages and races can experience. The cause of potential pain in your abdomen, this discomfort can be traced back to the inflammation which is associated with non-alcoholic fatty liver disease. Fortunately, a new study has revealed that a certain vitamin can help fight this inflammation.
In a study recently published in the Journal of Hepatology, a team from Duke-NUS Medical School in Singapore used both vitamin B12 and folate to examine their effect on non-alcoholic steatohepatitis (NASH), a type of non-alcoholic fatty liver disease. The results showed a reduction of inflammation and scarring caused by non-alcoholic fatty liver disease as well as a reduction in disease progression when taking vitamin B12 and folate supplements.
“Our findings are both exciting and important because they suggest that a relatively inexpensive therapy, vitamin B12 and folic acid, could be used to prevent and/or delay the progression of NASH,” said the study investigator. Brijesh Singh, PhDwith Duke-NUS Medical School in Singapore, via ScienceDaily.
How can vitamin B12 and folate help with non-alcoholic fatty liver disease?
“Non-alcoholic fatty liver disease is fatty buildup in the liver that is not caused by alcohol consumption. In some people, this causes inflammation and ultimately scarring in the most severe subtype of NAFLD, called NASH”, Leanne Poston MD, MBA, MEdof Invigor Medicalrecount Eat this, not that!. Dr. Poston explains that as non-alcoholic fatty liver disease progresses, “healthy liver cells are replaced by scar tissue.”
She also notes that a “recent clinical study found that the underlying cause of NASH is when Syntaxin 17 is degraded and prevented from shedding these dead and damaged cells.”
Syntaxin 17 is a protein whose role is to transport and digest fats, which supports healthy energy metabolism and the prevention of inflammation. In people with NASH, syntaxin 17 is prevented from doing its job.
When it comes to how vitamin B12 and folate helps with inflammation and scarring related to non-alcoholic fatty liver disease, Dr. Poston explains that they “increase levels of syntaxin 17 restoring its function, which reverses inflammation and scarring liver”.
If you want to increase the amount of B12 and folate you get in your diet, Dr. Polson says the former “is found in meat, fish, and dairy products,” while the latter can be “found in eggs”. , legumes and green leafy vegetables. »
Desirée O is a freelance writer who covers, among other things, lifestyle, food and nutrition news. Read more